Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure
| dc.contributor.author | Robeva, R. | |
| dc.contributor.author | Todorov, T. | |
| dc.contributor.author | Dimitrova, V. | |
| dc.contributor.author | Yordanov, M. | |
| dc.contributor.author | Doychinov, D. | |
| dc.date.accessioned | 2014-02-07T10:53:19Z | |
| dc.date.available | 2014-02-07T10:53:19Z | |
| dc.date.issued | 2011-10 | |
| dc.description | Address for correspondence: Assoc. Prof. R. Robeva, MD; Univ. Hosp. ”St . Ivan Rilski”; Dialysis and Clinical Pharmacology; 15, Blvd.” Acad. Ivan Geshov”; 1431 Sofia; tel. +35928510846 | en_US |
| dc.description.abstract | More than 140 years ago, fi rst Virchow associated observed lipid abnormalities with the concomitant renal disease. Despite a large body of clinical and laboratory evidence, the precise role of the lipids in the development of the renal disease remains unclear. In 1988, D. Doychinov described a new autosomal dominant hereditary disease leading to cholesterol accumulation within the glomerular mesangium. We report the case of a young man (a member of the affected family) with the same biopsy proven disease but with different clinical abnormalities and course. This patient had an overt nephrotic syndrome from the onset: 5 g/24h proteinuria, hypoproteinemia (52 g/l), hypoalbuminemia (28 g/l), hypercholesterolemia (8.5 mmol/l), edema as well as severe hypertension (180-200/110-120 mm Hg). Five years later he developed renal failure and after another three he was put on hemodialysis. | en_US |
| dc.identifier.citation | R. Robeva, T. Todorov, V. Dimitrova, M. Yordanov and D. Doychinov. Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure - Acta medica bulgarica , 38, 2011, No 2, 62-66. | en_US |
| dc.identifier.issn | 0324-1750 | |
| dc.identifier.uri | http://hdl.handle.net/10861/430 | |
| dc.language.iso | en | en_US |
| dc.publisher | Централна медицинска библиотека, МУ София / Central Medical Library - MU Sofia | en_US |
| dc.subject | mesangial lipoidosis, nephrotic syndrome, renal insuffi ciency | en_US |
| dc.title | Mesangial lipoidosis with cholesterol deposition – a new case with nephrotic syndrome and rapidly progressing renal failure | en_US |
| dc.type | Article | en_US |