Genetic aberrations in adult CD10 positive/cytoplasmic IgM negative B-cell acute lymphoblastic leukemia
| dc.contributor.author | Velizarova, M. | |
| dc.contributor.author | Popova, D. | |
| dc.contributor.author | Hadzhiev, E. | |
| dc.contributor.author | Dimova, I. | |
| dc.date.accessioned | 2015-07-08T12:09:32Z | |
| dc.date.available | 2015-07-08T12:09:32Z | |
| dc.date.issued | 2013-06 | |
| dc.description | Address for correspondence: Dr. Milena Velizarova; Department of Clinical Laboratory and Clinical Immunology; University Hospital Aleksandrovska; 1 G. Sofiyski St.; 1431 Sofia, Bulgaria; e-mail: mvelizarova@abv.bg | en_US |
| dc.description.abstract | In the recent years progress in the basic laboratory science has allowed for implementation of many advanced methods in the clinical practice. Flow cytometry is a method, which is most commonly used for clinical diagnosis of ‘de novo’ acute leukemias, and in combination with molecular-cytogenetic studies provides more opportunities for determination of patients’ risk factors and disease prognosis. We report on high percentage of adult CD10(+)/cyIgM(-) B-cell acute lymphoblastic leukemia (56% of all studied B-ALL) and unusual for this group chromosome findings - (8q24)/C-MYC, trizomy 8, t(1;19), no ploidy changes and low t(9;22) frequency. | en_US |
| dc.identifier.citation | M. Velizarova, D. Popova, E. Hadzhiev and I. Dimova. Genetic aberrations in adult CD10 positive/cytoplasmic IgM negative B-cell acute lymphoblastic leukemia - Acta medica bulgarica , 40, 2013, No 1, 3-9. | en_US |
| dc.identifier.issn | 0324-1750 | |
| dc.identifier.uri | http://hdl.handle.net/10861/655 | |
| dc.language.iso | en | en_US |
| dc.publisher | Централна медицинска библиотека - МУ София / Central medical Library - MU Sofia | en_US |
| dc.subject | cytogenetics, adult acute lymphoblastic leukemia, CD10(+) acute leukemia | en_US |
| dc.title | Genetic aberrations in adult CD10 positive/cytoplasmic IgM negative B-cell acute lymphoblastic leukemia | en_US |
| dc.type | Article | en_US |